2 products were found matching "2351820-19-2"!

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Item number: TGM-T73527-10mg

Description: GK563, a selective Ca 2+-independent phospholipase A2 (GVIA iPLA2) inhibitor, exhibits a potent IC50 value of 1 nM and demonstrates 22,000-fold greater activity against GVIA iPLA2 compared to GIVA cPLA2. Its efficacy in reducing beta-cell apoptosis triggered by proinflammatory cytokines suggests...

Application:	iPLA2beta inhibitor
CAS	2351820-19-2
MW:	246.34 D

From 233.00€ *

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(±)-trans-GK563

Item number: Cay25732-1

trans-(±)-GK563 is a potent beta-lactone inhibitor of group VIA (GVIA) calcium-independent phospholipase A2 (GVIA iPLA2, IC50 = 1 nM). It is selective for GVIA iPLA2 over GVIA cPLA2 (IC50 = 22 µM). trans-(±)-GK563 (1 and 10 µM) inhibits apoptosis induced by IL-1beta and IFN-gamma in INS-1 beta-cells.Formal Name:...

Keywords:	GK563, (3R,4R)-rel-3-(4-phenylbutyl)-4-propyl-2-oxetanone
Application:	iPLA2beta inhibitor
CAS	2351820-19-2
MW:	246.3 D

From 128.00€ *

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