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CAY10749
CAY10749

Item number: Cay30058-1

CAY10749 is a dual inhibitor of poly(ADP-ribose) polymerase (PARP) and PI3K (IC50s = 6.03, 3.63, 5.62, and 7.41 nM for PARP1, PARP2, PI3Kalpha, and PI3Kdelta, respectively). It is selective for these enzymes over PI3Kbeta and PI3Kgamma (IC50s = 288.4 and 831.76 nM, respectively), as well as a panel of 374 additional...
Keywords: 4-[[3-[[2-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-5,8-dihydro-4-(4-morpholinyl)pyrido[3,4-d]pyrimidin-7(6H)-yl]carbonyl]...
Application: PARP / PI3K dual inhibitor
CAS 2337386-47-5
MW: 660.6 D
From 187.00€ *
Review
PARP/PI3K-IN-1
PARP/PI3K-IN-1

Item number: TGM-T12365-100mg

Description: PARP/PI3K-IN-1 is a novel dual poly (ADP-ribose) polymerase (PARP) and phosphatidylinositol 3-kinase (PI3K) dual inhibitor with anticancer, antitumour and antiproliferative activities for the study of breast, pancreatic and lung cancers. Target: PI3K, PARP. Smiles:...
Application: PARP / PI3K dual inhibitor
CAS 2337386-47-5
MW: 660.62 D
From 93.00€ *
Review