Nivalenol is a trichothecene mycotoxin that has been found in Fusarium. It is lethal to mice (LD50 = 6.9 mg/kg). Nivalenol (5, 10, and 15 mg/kg) also induces thymic, splenic, and Peyer's patch cell apoptosis in mice.Formal Name: (3alpha,4beta,7alpha)-12,13-epoxy-3,4,7,15-tetrahydroxy-trichothec-9-en-8-one. CAS...

Nivalenol is a type - B trichothecene mycotoxin, produced by molds such as Fusarium cerealis, Fusarium graminearum. It is an apoptosis inducer, inhibits protein synthesis and nucleic acid synthesis in vitro.

Description: Nivalenol is a fungal metabolite produced by Fusarium graminearum. Nivalenol induces cell death through caspase and intrinsic apoptotic pathways thus affecting the immune system and causing emesis, growth retardation, and reproductive disorders. Target: Caspase. Smiles:...