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Item number: Cay42726-10

TR-14035 is a dual alpha4beta7 and alpha4beta1 integrin antagonist. It inhibits cell adhesion induced by the alpha4beta7 and alpha4beta1 integrin ligand fibronectin connecting segment 1 (FNCS1) in RPMI-8866 and Jurkat cells, which endogenously express alpha4beta7 and alpha4beta1, respectively (IC50s = 7 and 87 nM,...

Keywords:	aS-[(2,6-dichlorobenzoyl)amino]-2',6'-dimethoxy-[1,1'-biphenyl]-4-propanoic acid
Application:	Dual alpha4beta7 / alpha4beta1 integrin antagonist
CAS	232271-19-1
MW:	474.33 D

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TR-14035

Item number: TGM-T5310-100mg

Description: TR-14035 (MDK-1191) is a dual antagonist of alpha4beta7/alpha4beta1 integrins (IC50s: 7/87nM). Target: Integrin. Smiles: COc1cccc(OC)c1-c1ccc(C[C@H](NC(=O)c2c(Cl)cccc2Cl)C(O)=O)cc1. References: Tsuda-Tsukimoto M, et al. Characterization of hepatobiliary transport systems of a novel...

Keywords:	MDK-1191
CAS	232271-19-1
MW:	474.33 D

From 46.00€ *

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