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Item number: Cay44278-1

Lepzacitinib is an inhibitor of JAK1 and JAK3 (IC50s = 1.5 and 3.6 nM, respectively). It selectively inhibits IL-2-induced activation of JAK1/3 over IFN-gamma-induced activation of JAK1/2, GM-CSF-induced activation of JAK2, and IL-12-induced activation of JAK2/tyrosine kinase 2 (TYK2) in isolated human peripheral...

Keywords:	ATI-1777, 4-[[(3R)-1-(2-cyanoacetyl)-3-piperidinyl]amino]-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid, ethyl ester
Application:	JAK1 / JAK3 inhibitor
CAS	2321488-47-3
MW:	355,4 D

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