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Item number: Cay15526-1

ALK5 inhibitor II is a cell permeable, selective inhibitor of the TGF-beta type 1 activin like kinase receptor ALK5 (IC50s = 4, 18, and 23 nM for ALK5 autophosphorylation, TGF-beta cellular assay, and ALK5 binding in HepG2 cells, respectively). This inhibitor demonstrated less potent activity (IC50s > 16 µM) when...

Keywords:	E 616452, RepSox, SJN 2511, 2-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine, monohydrochloride
Application:	TGFBR1 inhibitor
CAS	2319939-07-4
MW:	323.8 D

From 50.00€ *

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ALK5 Inhibitor II (hydrochloride)

Item number: TGM-T22560-10mg

Description: ALK5 Inhibitor II is an ALK5 inhibitor. IC50: 4, 18, and 23 nM for ALK5 autophosphorylation, TGF-beta cellular assay, and ALK5 binding in HepG2 cells, respectively. Target: Others. Smiles: CC1=NC(C2=NNC=C2C3=NC4=CC=CN=C4C=C3)=CC=C1.Cl

Application:	ALK5 inhibitor
CAS	2319939-07-4
MW:	323.8 D

From 113.00€ *

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