AGPS-IN-2i is an inhibitor of alkyldihydroxyacetonephosphate synthase (alkyl-DHAP synthase). It decreases levels of nine ether phospholipids in 231MFP breast cancer cells when used at a concentration of 500 µM. AGPS-IN-2i reduces migration of, and induces cytotoxicity in, 231MFP cells. InChI:...

Description: AGPS-IN-2i is a potent and high-affinity inhibitor of alkylglycerol phosphate synthase that controls ether lipid utilization and metabolism in cells, reduces ether lipid levels and cell migration, and promotes proliferation and motility of cancer cells. AGPS-IN-2i had an inhibitory effect on cancer cell...