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Item number: TGM-T9753-10mg

Description: LEI110 is a potent Phospholipase A2, group XVI (PLA2G16) inhibitor with an Ki value of 20 nM. LEI110 is a selective pan-inhibitor of the HRASLS family of thiol hydrolases (i.e., PLA2G16, HRASLS2, RARRES3 and iNAT). Target: Phospholipase. Smiles: FC(F)(F)c1ccc(Oc2ccc(CCNC(=O)C(=O)CCCc3ccccc3)cc2)nc1....

Application:	PLAAT3 (AdPLA) inhibitor
CAS	2313525-90-3
MW:	456.46 D

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LEI-110

Item number: Cay36789-1

LEI-110 is an inhibitor of adipose phospholipase A2 (AdPLA2, IC50 = 100 nM). It also inhibits HRas-like suppressor 2 (HRASL2), retinoid acid receptor responder protein 3 (RARRES3), and calcium-independent N-acyltransferase (iNAT, IC50s = 158, 158, and 25 nM, respectively). LEI-110 (10 µM) decreases arachidonic acid...

Keywords:	alpha-oxo-N-[2-[4-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]ethyl]-benzenepentanamide
Application:	PLAAT3 (AdPLA) inhibitor
CAS	2313525-90-3
MW:	456.5 D

From 120.00€ *

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