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UK 356618
UK 356618

Item number: TGM-T17201-10mg

Description: UK 356618 is a potent and selective inhibitor of matrix metalloprotease-3 (IC50: 5.9 nM). Target: MMP. Smiles: C[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCc1ccc(c(C)c1)-c1ccccc1)CC(=O)NO)C(C)(C)C)c1ccccc1
Application: MMP3 inhibitor
CAS 230961-08-7
MW: 557.72 D
From 295.00€ *
Review
UK 356618
UK 356618

Item number: Cay32859-5

UK 356618 is an inhibitor of matrix metalloproteinase-3 (MMP-3, IC50 = 5.9 nM). It is selective for MMP-3 over MMP-1, -2, -9, -13, and -14 (IC50s = 51, 1.79, 0.84, 0.073, and 1.9 µM, respectively). UK 356618 (73 nM) inhibits IL-6-induced migration of NCI H446 small cell lung cancer (SCLC) cells in vitro. It reduces...
Keywords: (2R)-N1-[(1S)-2,2-dimethyl-1-[[[(1R)-1-phenylethyl]amino]carbonyl]propyl]-N4-hydroxy-2-[3-(2-methyl[1,1'-biphenyl]-4-yl)pr...
Application: MMP3 inhibitor
CAS 230961-08-7
MW: 557.7 D
From 166.00€ *
Review