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Lofepramine
Lofepramine

Item number: TGM-T15773-100mg

Description: Lofepramine (Leo 640) is a potent tricyclic antidepressant that is extensively metabolized to desipramine. It inhibits the serotonin and norepinephrine transporters by inhibiting neurons with Kd values of 70 and 5.4 nM, respectively, with weak antagonism of serotonin, histamine and muscarinic receptors....
Keywords: Lopramine, Amplit, Leo 640, Gamanil
Application: Targets solute carrier family 6 (neurotransmitter transporter, serotonin) member 4 (SLC6A4, SERT)
CAS 23047-25-8
MW: 418.96 D
From 42.00€ *
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Lofepramine
Lofepramine

Item number: Cay20813-1

Lofepramine is a first generation tricyclic antidepressant that is extensively metabolized to desipramine. It potently inhibits serotonin and norepinephrine transporters (Kds = 70 and 5.4 nM, respectively) and less potently antagonizes serotonin, histamine, and muscarinic receptors.Formal Name:...
Keywords: Lopramine, 1-(4-chlorophenyl)-2-[[3-(10,11-dihydro-5H-dibenz[b,f]azepin-5-yl)propyl]methylamino]-ethanone
Application: Antidepressant, serotonin-noradrenaline reuptake inhibitor (SNRI)
CAS 23047-25-8
MW: 419 D
From 44.00€ *
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