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Item number: Cay43035-10

GFB-8438 is an inhibitor of transient receptor potential canonical 5 (TRPC5, IC50 = 0. µM). It is selective for TRPC5 over TRPC6 and voltage-gated sodium channel 1. (Nav1.5, IC50s = >30 µM for both) and a panel of 100 receptors and kinases at 10 µM but does inhibit TRPC4 (IC50 = 0. µM). GFB-8438 (30 mg/kg per day)...

Keywords:	4-chloro-5-[3-oxo-4-[[2-(trifluoromethyl)phenyl]methyl]-1-piperazinyl]-3(2H)-pyridazinone
Application:	TRPC5 inhibitor
CAS	2304549-73-1
MW:	386.76 D

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