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Item number: Cay45371-1

ATR-258 is a GRK-biased agonist of the beta2-adrenergic receptor (beta2-AR). It binds to the orthosteric site on beta2-AR and mediates glucose uptake dependent on G protein-coupled receptor kinase 2 (GRK2) with low Galphas-dependent cAMP generation in a phenotypic screen. ATR-258 (10 µM) increases glucose uptake in...

Keywords:	alphaR-[[(1,1-dimethylethyl)amino]methyl]-5-fluoro-3-pyridinemethanol
Application:	Beta2-AR GRK-biased agonist
CAS	2301983-88-8
MW:	212.27 D

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