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Item number: Cay23932-10

TAS 102 is an orally bioavailable combination of the antimetabolite nucleoside analog trifluorothymidine (TFT, Cay-21366) with the thymidine phosphorylase (TPase) inhibitor tipiracil (TPI, Cay-23319). In vivo, TAS 102 inhibits tumor growth by 65.7 and 44.9% in HCT116 and KM12C colon cancer xenograft mouse models,...

Keywords:	alpha,alpha,alpha-trifluoro-thymidine mixt. with 5-chloro-6-[(2-imino-1-pyrrolidinyl)methyl]-2,4(1H,3H)-pyrimidinedione,...
Application:	Antineoplastic, antimetabolite, antiviral (Trifluridine - tipiracil hydrochloride mixt)
CAS	2300074-31-9
MW:	435.8 D

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