Neferine is an alkaloid that has been found in N. nucifera and has diverse biological activities. It inhibits ADP-, collagen-, thrombin-, U46619-, or adrenaline-induced aggregation of isolated human platelets when used at a concentration of 3 µM. Neferine (2 µM) prevents LPS- and ATP-induced pyroptosis, NLRP3...

Description: 1. Neferine ((-)-Neferine) has anti-tumor activities , Metabolic activation mediated by CYP3A4 and GSH depletion enhanced Neferine-induced cytotoxicity. 2. Neferine can be helpful to increase the efficacy of DOX and to achieve anticancer synergism by curbing the toxicity. 3. Neferine inhibited high...