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EP4 receptor antagonist 1
Item number: TGM-T11211-10mg
Description: EP4 Receptor Antagonist 1 is a highly potent and selective competitive prostanoid EP4 receptor antagonist, effective for cancer immunotherapy. It inhibits both human and mouse EP4 receptors with IC50 values of 6.1 nM and 16.2 nM, respectively, while displaying minimal activity (IC50s >10 µM) against...
| CAS | 2287259-07-6 |
| MW: | 458.43 D |
From 106.00€
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EP4 Receptor Antagonist 1
Item number: Cay32722-5
EP4 receptor antagonist 1 is an antagonist of the prostaglandin E2 (PGE2) receptor EP4 that has an IC50 value of 6.1 nM in a calcium flux assay using CHO cells co-expressing the human receptor and Galpha16. It is selective for EP4 over EP1, EP2, and EP3 receptors (IC50s = >10,000 nM for all). EP4 receptor antagonist...
| Keywords: | 4-[(1S)-1-[[[4-(1E)-1-propen-1-yl-1-[[4-(trifluoromethyl)phenyl]methyl]-1H-1,2,3-triazol-5-yl]carbonyl]amino]ethyl]-benzoi... |
| Application: | EP4 receptor antagonist |
| CAS | 2287259-07-6 |
| MW: | 458.4 D |
From 94.00€
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