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ABBV-467
ABBV-467

Item number: Cay44289-1

ABBV-467 is an inhibitor of myeloid cell leukemia-1 (Mcl-1, Ki = 642, >376, >247, and >402 nM, respectively). ABBV-467 reduces the viability of AMO1, NCI H929, and MV4-11 myeloma cells (EC50s = 0. 0. and 3. nM, respectively). In vivo, ABBV-467 (3. 6. and 12. mg/kg) reduces tumor growth in an AMO1 mouse xenograft...
Keywords: (7R,16R)-19,23-dichloro-10-[[2-[4-[(2R)-1,4-dioxan-2-ylmethoxy]phenyl]-4-pyrimidinyl]methoxy]-1-(4-fluorophenyl)-7,8,15,16...
Application: Mcl-1 inhibitor
CAS 2287186-66-5
MW: 1037.98 D
364.00€ *
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