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CSF1R-IN-2
CSF1R-IN-2

Item number: TGM-T13194-100mg

Description: CSF1R-IN-2 is an oral-active SRC, MET and c-FMS inhibitor (IC50s: 0.12 nM, 0.14 nM and 0.76 nM for SRC, MET and c-FMS respectively). Target: c-Fms, c-Met/HGFR, Src. Smiles: CCN1Cc2c(O[C@@H](C)CNC(=O)c3c(N)nn4ccc1nc34)ccc(F)c2C#N. References: WO 2019023417 A1.
Application: Targets proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1] (MET, HGFR)
CAS 2271119-26-5
MW: 409.42 D
From 40.00€ *
Review
TPX-0022
TPX-0022

Item number: Cay36118-1

TPX-0022 is an inhibitor of Src, MET, and CSF-1 receptor tyrosine kinase (FMS) kinases (IC50s = 0.12, 0.14, and 0.76 nM, respectively). It inhibits the proliferation of MKN45 and SNU-5 human gastric cancer cells (IC50s = 0.2 and 0.17 nM, respectively), as well as Ba/F3 pro-B cells expressing TEL-CSF1R (IC50 = 19.3...
Keywords: CSF1R Inhibitor 2, CSF1R-IN-2, Elzovantinib,...
Application: Src / MET / FMS kinase inhibitor
CAS 2271119-26-5
MW: 409.4 D
From 53.00€ *
Review