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Item number: Cay43812-10

DS9300 is an inhibitor of histone acetyltransferase p300 (IC50 = 28 nM). It inhibits acetylation of lysine 27 on histone H3 (H3K27) in LK-2 cells (IC50 = 54 nM). DS9300 inhibits the growth of VCaP prostate cancer cells (GI50 = 0.6 nM). In vivo, DS9300 (0.3-3 mg/kg) reduces tumor volume in a VCaP castrated mouse...

Keywords:	(2R,4R)-1-[[4,4-difluoro-1-(4-methoxyphenyl)cyclohexyl]carbonyl]-4-fluoro-N-1H-pyrazolo[4,3-b]pyridin-5-yl-2-pyrrolidineca...
Application:	p300 (CREBBP) inhibitor
CAS	2259641-46-6
MW:	501.51 D

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DS-9300

Item number: TGM-T73459-100mg

Description: DS-9300, an orally administered potent and selective inhibitor of EP300/CBP HAT, exhibits a significant inhibitory activity with an IC50 value of 28 nM. Demonstrating anticancer properties, it is utilized in research focused on prostate cancer disease. Target: Others. Smiles:...

CAS	2259641-46-6
MW:	501.5 D

From 2,152.00€ *

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