2 products were found matching "2257427-45-3"!
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TSI-13-57
Item number: Cay45498-1
An inhibitor of Mal homodimerization and TLR signaling, inhibits the secretion of TNF-alpha induced by agonists of TLR9, -7, -2, or -4 in RAW 264.7 macrophages (IC50s = 2.7, 6.03, 7.37, and 6.38 µM, respectively), reduces LPS-induced increases in TNF-alpha levels in mouse plasma at 100 and 200 mg/kg. SMILES:...
| Keywords: | 4,4'-[3-[4-[2-(1-piperidinyl)ethoxy]phenyl]-1H-pyrazole-1,5-diyl]bis-phenol |
| Application: | MAL (TIRAP) homodimerization / TLR signaling inhibitor |
| CAS | 2257427-45-3 |
| MW: | 455.56 D |
From 402.00€
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TSI-13-57
Item number: TGM-T69719-100mg
Description: TSI-13-57 is a MyD88 inhibitor. Target: Others. Smiles: OC1=CC=C(C=2N(N=C(C2)C3=CC=C(OCCN4CCCCC4)C=C3)C5=CC=C(O)C=C5)C=C1
| CAS | 2257427-45-3 |
| MW: | 455.55 D |
From 1,440.00€
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