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Item number: Cay45369-10

BMS 986235 is a formyl peptide receptor 2 (FPR2) agonist. It selectively induces calcium mobilization in HEK293 cells overexpressing human FPR2 over FPR1 (EC50s = 0.41 and 2,800 nM, respectively). BMS 986235 inhibits chemotaxis of HL-60 human promyeloblast cells and induces phagocytosis of opsonized zymosan by...

Keywords:	LAR-1219, N-[(3S,4R)-4-(2,6-difluoro-4-methoxyphenyl)-2-oxo-3-pyrrolidinyl]-N'-phenyl-urea
Application:	FPR2 agonist
CAS	2253947-47-4
MW:	361.35 D

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BMS-986235

Item number: TGM-T39789-100mg

Description: BMS-986235 (LAR-1219) is a selective and orally active agonist of formyl peptide receptor 2 (FPR2) with EC50s of 0.41 nM for hFPR2 and 3.4 nM for mFPR2. BMS-986235 can be used in studies on the prevention of heart failure. Target: Others. Smiles: COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccccc2)c(F)c1....

Keywords:	LAR-1219, BMS-986235
CAS	2253947-47-4
MW:	361.34 D

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