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CCT369260
Item number: Cay41314-10
CCT369260 is a degrader of Bcl-6. It induces degradation of Bcl-6 in SU-DHL-4, OCI-LY1, and Karpas-422 cells with half-maximal degradation concentration (DC50) values of 0.09, 0.049, and 0.062 µM, respectively. CCT369260 inhibits the growth of SU-DHL-4, OCI-LY1, and OCI-Ly3 cancer cells (GI50s = 0.092, 0.035, and...
| Keywords: | rel-5-[[5-chloro-2-[(3R,5S)-4,4-difluoro-3,5-dimethyl-1-piperidinyl]-4-pyrimidinyl]amino]-1,3-dihydro-3-(3-hydroxy-3-methy... |
| Application: | Bcl-6 degrader |
| CAS | 2253878-44-1 |
| MW: | 509 D |
From 267.00€
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BCL6-IN-3
Item number: TGM-T10487-100mg
Description: BCL6-IN-3 is a potent BCL6 inhibitor with GI50 of 70 nM in SU-DHL4 cells. BCL6-in-3 regulates cell activation, differentiation, DNA damage and apoptosis, and has antitumor activity. Target: Others, BCL, DNA. Smiles: C(CC(C)(C)O)N1C=2C(N(C)C1=O)=CC=C(NC3=NC(=NC=C3Cl)N4C[C@H](C)C(F)(F)[C@H](C)C4)C2....
| CAS | 2253878-44-1 |
| MW: | 508.99 D |
From 117.00€
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