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Cathepsin Inhibitor 1
Cathepsin Inhibitor 1

Item number: Cay28790-1

Cathepsin inhibitor 1 is an inhibitor of cathepsin L (IC50 = 12. nM). It is selective for cathepsin L over cathepsin L2, cathepsin S, cathepsin K, and cathepsin B (IC50s = 199. 1,000, 3,162. and 6,309. nM, respectively).. Solulibility: DMSO: Soluble: = 10 mg/ml: Ethanol: Soluble: = 10 mg/ml.
Keywords: N-[(1S)-1-[(3-chlorophenyl)methyl]-2-[(cyanomethyl)amino]-2-oxoethyl]-3-(1,1-dimethylethyl)-1-methyl-1H-pyrazole-5-carboxa...
Application: Cathepsin L inhibitor
CAS 225120-65-0
MW: 401.88976 D
From 38.00€ *
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Cathepsin Inhibitor 1
Cathepsin Inhibitor 1

Item number: TGM-T6015-100mg

Description: Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively. Target: Cysteine Protease. Smiles: Cn1nc(cc1C(=O)NC(Cc1cccc(Cl)c1)C(=O)NCC#N)C(C)(C)C. References: Asaad N, et al. Bioorg Med Chem Lett, 2009, 19(15), 4280-4283.
Application: Cathepsin inhibitor
CAS 225120-65-0
MW: 401.89 D
From 39.00€ *
Review