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Item number: TGM-T35928-1mg

Description: NVS-PAK1-1 is a potent allosteric inhibitor of PAK1 with an IC 50 of 5 nM for dephosphorylated PAK1 and 6 nM for phosphorylated PAK1 as assessed. Inhibition is ATP-competitive, most likely due to indirect competition due to incompatibility of ATP binding with the DFG-out binding conformation of the...

Keywords:	NVS-PAK1-C
Application:	Negative control
CAS	2250019-95-3
MW:	465.9 D

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NVS-PAK1-C

Item number: Cay19965-1

NVS-PAK1-C is a negative control for the allosteric PAK1 inhibitor NVS-PAK1-1 (Cay-19964). See the Structural Genomic Consortium (SGC) website for more information.Formal Name: (3S)-(3-[[2-chloro-5-(2,2-difluoroethyl)-8-fluoro-5H-dibenzo[b,e][1,4]diazepin-11-yl]amino]-N,N-dimethyl-1-pyrrolidinecarboxamide. CAS...

Keywords:	(S)-3-((2-chloro-5-(2,2-difluoroethyl)-8-fluoro-5H-dibenzo[b,e][1,4]diazepin-11-yl)amino)-N,N-dimethylpyrrolidine-1-carbox...
Application:	Negative control
CAS	2250019-95-3
MW:	465.9 D

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