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SN-011
SN-011

Item number: LKT-S520011.1

SN-011 is an inhibitor of STING. SMILES: C1=CC=C(C=C1)C2=CC=C(C=C2)C(=O)NC3=CC(=C(C=C3)O)NS(=O)(=O)C4=CC=C(C=C4)F
Keywords: GUN35901, SN011, N-[3-[(4-fluorophenyl)sulfonylamino]-4-hydroxyphenyl]-4-phenylbenzamide
Application: STING antagonist
CAS 2249435-90-1
MW: 462.5 D
From 69.00€ *
Review
SN-011
SN-011

Item number: TGM-T9137-100mg

Description: SN-011 (GUN35901) is a STING inhibitor, which inhibited the activation of the STING signal pathway and to prevent or treat a STING- mediated disease. It is a demethyl analogue of DUN99845. Target: STING. Smiles: Oc1ccc(NC(=O)c2ccc(cc2)-c2ccccc2)cc1NS(=O)(=O)c1ccc(F)cc1
Keywords: GUN35901, [1,1'-Biphenyl]-4-carboxamide, N-[3-[[(4-fluorophenyl)sulfonyl]amino]-4-hydroxyphenyl]-
Application: STING antagonist
CAS 2249435-90-1
MW: 462.49 D
From 48.00€ *
Review
SN-011
SN-011

Item number: Cay34890-1

SN-011 is a stimulator of interferon genes (STING) antagonist. It binds to the STING cyclic dinucleotide binding site (Kd = 4.03 nM) and inhibits 2'3'-cGAMP-induced Ifnb expression in mouse embryonic fibroblasts (MEFs), mouse bone marrow-derived macrophages (BMDMs), and human foreskin fibroblasts (HFFs, IC50s =...
Keywords: GUN35901, N-[3-[[(4-fluorophenyl)sulfonyl]amino]-4-hydroxyphenyl]-[1,1'-biphenyl]-4-carboxamide
Application: STING antagonist
CAS 2249435-90-1
MW: 462.5 D
From 67.00€ *
Review