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BAY-6035
Item number: Cay25925-1
BAY-6035 is an inhibitor of SET and MYND domain-containing protein 3 (SMYD3). It is 100-fold selective for SMYD3 over other histone methyltransferases. BAY-6035 inhibits methylation of MEKK2 peptide in a cell-free assay and in cells (IC50s = 88 and 70 nM, respectively). See the Structural Genomic Consortium (SGC)...
| Keywords: | (2S)-1-(3-azabicyclo[3.1.0]hex-3-ylcarbonyl)-N-(2-cyclopropylethyl)-2,3,4,5-tetrahydro-2-methyl-4-oxo-1H-1,5-benzodiazepin... |
| Application: | SMYD3 inhibitor |
| CAS | 2247890-13-5 |
| MW: | 396.5 D |
From 51.00€
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BAY-6035
Item number: TGM-T36631-10mg
Description: BAY-6035 is an inhibitor of SET and MYND domain-containing protein 3 (SMYD3). BAY-6035 has more than 100-fold selectivity over other histone methyltransferases. Target: Histone Methyltransferase, MEK. Smiles: C[C@H]1CC(=O)Nc2cc(ccc2N1C(=O)N1CC2CC2C1)C(=O)NCCC1CC1. References: Edoardo F, et, al....
| Application: | SMYD3 inhibitor |
| CAS | 2247890-13-5 |
| MW: | 396.48 D |
From 30.00€
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