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CAY10746
Item number: TGM-T36196-100mg
Description: CAY10746 is a selective Rho kinase (ROCK) inhibitor, targeting ROCK I and ROCK II with IC50 values of 0.014 µM and 0.003 µM, respectively. CAY10746 can be employed in the study of diabetic retinopathy. Target: ROCK. Smiles: CN(C)c1ccc(cc1)C(=O)Nc1cccc(NC(=O)COc2ccc3c(c2)occc3=O)c1. References: Zhao L,...
| Application: | ROCK-I inhibitor, ROCK-II inhibitor |
| CAS | 2247240-76-0 |
| MW: | 457.48 D |
From 48.00€
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CAY10746
Item number: Cay29814-1
CAY10746 is an inhibitor of Rho-associated kinase I (ROCK1) and ROCK2 (IC50s = 14 and 3 nM, respectively). It is selective for ROCK1 and ROCK2 over PKA (IC50 = >10,000 nM) and over 387 recombinant human protein kinases in a panel of 394 kinases (IC50s = >10,000 nM for all) but does inhibit LIM kinase 2 (LIMK2),...
| Keywords: | 4-(dimethylamino)-N-[3-[[2-[(4-oxo-4H-1-benzopyran-7-yl)oxy]acetyl]amino]phenyl]-benzamide |
| Application: | ROCK-I inhibitor, ROCK-II inhibitor |
| CAS | 2247240-76-0 |
| MW: | 457.5 D |
From 209.00€
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