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Item number: TGM-T7138-100mg

Description: FB23-2 is a potent and selective inhibitor of the mRNA N6-methyladenosine (m6A) demethylase FTO with an IC50 of 2.6 µM. Target: Apoptosis, Others. Smiles: Cc1noc(C)c1-c1cc(Cl)c(Nc2ccccc2C(=O)NO)c(Cl)c1. References: Huang Y , Su R , Sheng Y , et al. Small-Molecule Targeting of Oncogenic FTO Demethylase...

Application:	FTO inhibitor
CAS	2243736-45-8
MW:	392.24 D

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FB23-2

Item number: Cay36606-5

FB23-2 is an inhibitor of the mRNA N6-methyladenosine (m6A) demethylase fat mass and obesity-associated (FTO) protein (IC50 = 2.6 µM). It reduces the proliferation of NB4 and Mono-Mac-6 cells (IC50s = 0.8 and 1.5 µM, respectively). FB23-2 increases m6A levels in isolated human bone marrow cells, as well as...

Keywords:	2-[[2,6-dichloro-4-(3,5-dimethyl-4-isoxazolyl)phenyl]amino]-N-hydroxy-benzamide
Application:	FTO inhibitor
CAS	2243736-45-8
MW:	392.2 D

From 87.00€ *

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