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Mirabegron
Mirabegron

Item number: TGM-T1671-100mg

Description: Mirabegron (YM178) is a beta-3 adrenergic agonist that is used for treatment of overactive bladder syndrome. Target: Adrenergic Receptor. Smiles: N(C(CC1=CSC(N)=N1)=O)C2=CC=C(CCNC[C@H](O)C3=CC=CC=C3)C=C2. References: Takasu T, et al. J Pharmacol Exp Ther, 2007, 321(2), 642-647.
Keywords: YM178
Application: Targets adrenergic receptor beta-3 (ADRB3)
CAS 223673-61-8
MW: 396.51 D
From 31.00€ *
Review
Mirabegron
Mirabegron

Item number: Cay17319-10

Mirabegron is an agonist of the beta3-adrenergic receptor (beta3-AR). It induces cAMP accumulation in CHO cells expressing the beta3-AR but not the beta1- or beta2-AR (EC50s = 0.0224, >10, and >10 µM, respectively). Mirabegron reduces contraction induced by carbamoylcholine (Cay-14486) of isolated rat and human...
Keywords: YM-178, 2-amino-N-[4-[2-[[(2R)-2-hydroxy-2-phenylethyl]amino]ethyl]phenyl]-4-thiazoleacetamide
Application: beta3-adrenergic receptor agonist
CAS 223673-61-8
MW: 396.5 D
From 52.00€ *
Review