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YM-58483
YM-58483

Item number: Cay13246-1

Calcium release-activated calcium (CRAC) channels mediate sustained calcium influx in electrically non-excitable cells. CRAC channels are activated by the release of calcium from intracellular stores, as induced by inositol trisphosphate. CRAC channel activation is essential for the activation of leukocytes and the...
Keywords: BTP 2, N-[4-[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-4-methyl-1,2,3-thiadiazole-5-carboxamide
Application: CRAC channel inhibitor
CAS 223499-30-7
MW: 421.3 D
From 47.00€ *
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YM-58483
YM-58483

Item number: TGM-T3651-100mg

Description: YM-58483 (BTP2) is a specific and effective inhibitor of CRAC channels and subsequent Ca2+ signals. Target: Calcium Channel. Smiles: Cc1nnsc1C(=O)Nc1ccc(cc1)-n1nc(cc1C(F)(F)F)C(F)(F)F. References: Ohga K, et al. Int Immunopharmacol. 2008, 8(13-14):1787-92.
Keywords: YM 58483, BTP2
Application: CRAC channel inhibitor
CAS 223499-30-7
MW: 421.32 D
From 31.00€ *
Review