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GRP94 Inhibitor 1
Item number: Cay43140-10
GRP94 inhibitor 1 is a ligand of glucose-regulated protein 94 (GRP94, IC50 = 2 nM in a fluorescence polarization assay). It decreases the levels of integrin alpha2 and integrin alphaL in PANC-1 cells when used at concentrations of 2. or 5 µM. GRP94 inhibitor 1 (10 or 30 mg/kg twice per day) increases body weight,...
| Keywords: | 4-[(trans-4-hydroxycyclohexyl)amino]-4'-(1-methylethyl)-[1,1'-biphenyl]-3-carboxamide |
| Application: | GRP94 (glucose-regulated protein 94, endoplasmin, HSP90B1) ligand |
| CAS | 2234897-35-7 |
| MW: | 352.48 D |
From 73.00€
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Grp94 Inhibitor-1
Item number: TGM-T7261-100mg
Description: Grp94 Inhibitor-1 is a potent and selective inhibitor of Grp94 with an IC50 of 2 nM. Target: GPCR, HSP. Smiles: CC(C)c1ccc(cc1)-c1ccc(N[C@H]2CC[C@H](O)CC2)c(c1)C(N)=O. References: Jiang F , Guo A P , Xu J C , et al. Discovery of a Potent Grp94 Selective Inhibitor with Anti-inflammatory Efficacy in a...
| Application: | Grp94 inhibitor |
| CAS | 2234897-35-7 |
| MW: | 352.47 D |
From 39.00€
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