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Item number: Cay42727-1

Evatanepag is an agonist of prostaglandin E2 (PGE2) receptor subtype EP2. It induces cAMP accumulation in cells expressing rat EP2 (EC50 = 0. nM). Evatanepag (3 mg/kg) increases total bone area, mineral content, and mineral density in rat tibia.. Solulibility: DMSO: Sparingly soluble: 0.1-1 mg/ml: .

Keywords:	CP 533,536, 2-[3-[[[[4-(1,1-dimethylethyl)phenyl]methyl](3-pyridinylsulfonyl)amino]methyl]phenoxy]-acetic acid
Application:	Prostaglandin E2 receptor (EP2) agonist
CAS	223488-57-1
MW:	468.6 D

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Evatanepag

Item number: TGM-T15259-100mg

Description: Evatanepag (CP-533536 free acid) is an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation with EC50 of 0.3 nM.CP-533536 demonstrated the ability to heal fractures when administered locally as a single dose in rat models of fracture healing. Target: Prostaglandin...

Keywords:	CP-533536 free acid
Application:	Targets prostaglandin E receptor 2 (PTGER2)
CAS	223488-57-1
MW:	468.57 D

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