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MT-802
MT-802

Item number: Cay36581-25

MT-802 is a proteolysis-targeting chimera (PROTAC) composed of the Bruton's tyrosine kinase (BTK) inhibitor ibrutinib (Cay-16274) linked to the cereblon inhibitor pomalidomide (Cay-19877). It induces degradation of BTK in NAMALWA cells when used at concentrations ranging from 10 to 250 nM. MT-802 (1 µM) induces BTK...
Keywords: 2-[2-[2-[4-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]ethoxy]ethoxy]-N-[2-(2,6-dioxo-3-p...
Application: BTK degradation driving PROTAC
CAS 2231744-29-7
MW: 787.8 D
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