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Item number: Cay28158-5

PF-06869206 is an orally bioavailable inhibitor of sodium-phosphate cotransporter 2a (NaPi2a, IC50 = 380 nM). It is selective for NaPi2a over NaPi2b, NaPi2c, PiT-1, and PiT-2 (IC50s = >25 µM).Formal Name:...

Keywords:	3-chloro-7-[(2S)-2-(hydroxymethyl)-4-morpholinyl]-2-methyl-5-(trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine-6-carbonitrile
Application:	NaPi-2a inhibitor
CAS	2227425-05-8
MW:	374.7 D

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PF-06869206

Item number: TGM-TQ0011-100mg

Description: PF-06869206 is an oral selective inhibitor of the sodium-phosphate cotransporter NaPi2a (SLC34A1, IC50: 380 nM). Target: Sodium Channel. Smiles: Cc1[nH]c2c(N3CCO[C@H](CO)C3)c(C#N)c(nc2c1Cl)C(F)(F)F. References: Filipski KJ, et al. Discovery of Orally Bioavailable Selective Inhibitors of the...

Application:	NaPi-2a inhibitor
CAS	2227425-05-8
MW:	374.75 D

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