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KY19382
Item number: TGM-T9025-100mg
Description: KY19382 (2H-Indol-2-one, 5,6-dichloro-3-[1,3-dihydro-3-(methoxyimino)-2H-indol-2-ylidene]-1,3-dihydro-Ky19382) is a potent and orally active dual inhibitor of CXXC5-DVL and GSK3beta( IC50s of 19 and 10 nM, respectively). It activates Wnt/beta-catenin signaling through inhibitory effects on both...
| Keywords: | 2H-Indol-2-one, 5,6-dichloro-3-[1,3-dihydro-3-(methoxyimino)-2H-indol-2-ylidene]-1,3-dihydro-Ky19382, A3051 |
| Application: | CXXC5-Dvl protein-protein interaction inhibitor |
| CAS | 2226664-93-1 |
| MW: | 360.19 D |
From 100.00€
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KY 19382
Item number: Cay37579-1
KY 19382 is an inhibitor of the protein-protein interaction between CXXC-type zinc finger protein 5 (CF5) and Dishevelled (Dvl, IC50 = 19 nM). It is also an inhibitor of glycogen synthase kinase 3beta (GSK3beta, IC50 = 10 nM). KY 19382 (100 nM) increases expression of the mRNA encoding Wnt1-inducible signaling...
| Keywords: | 5,6-dichloro-3-[1,3-dihydro-3-(methoxyimino)-2H-indol-2-ylidene]-1,3-dihydro-2H-indol-2-one |
| Application: | CXXC5-Dvl protein-protein interaction inhibitor |
| CAS | 2226664-93-1 |
| MW: | 360.2 D |
From 81.00€
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