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LLY-284
LLY-284

Item number: Cay43141-1

LLY-284 is a diastereomer of the protein arginine methyltransferase 5 (PRMT5) inhibitor LLY-283 (Cay-21596). It weakly inhibits PRMT5 (IC50 = 1,074 nM). LLY-284 (100 µM) inhibits the asexual growth of P. falciparum in vitro.. Solulibility: DMSO: Soluble: = 10 mg/ml: Ethanol: Soluble: = 10 mg/ml.
Keywords: 7-[(5S)-5-C-phenyl-beta-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Application: Protein arginine methyltransferase 5 (PRMT5) inhibitor LLY-283 diastereomer
CAS 2226515-75-7
MW: 342.36 D
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LLY-284
LLY-284

Item number: TGM-T22356-25mg

Description: LLY-284, the diastereomer of LLY-283, serves as a selective and potent SAM-competitive chemical probe for PRMT5. Unlike the highly active LLY-283, LLY-284 exhibits significantly lower activity and is used as a negative control for LLY-283. Target: Others. Smiles:...
CAS 2226515-75-7
MW: 342.355 D
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