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Item number: Cay44845-1

Befotertinib is an inhibitor of mutant EGFRs. It selectively inhibits EGFRL858R, EGFRE709K, EGFRG719A, and EGFRL861Q (IC50s = 0. 14, 1. and 13 nM, respectively), as well as EGFR containing an exon 19 deletion and EGFR containing an exon 18 deletion (IC50s = 0. and 24 nM, respectively), over wild-type EGFR (IC50 =...

Keywords:	D-0316,...
Application:	Mutant EGFR inhibitor
CAS	2226167-02-6
MW:	663.72 D

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