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Item number: TGM-T15183-2mg

Description: Dynarrestin is a cytoplasmic dynein 1 and 2 aminothiazole inhibitor that reversibly inhibits dynein 1-driven microtubule sliding in vitro and intracellular dynein 1 and 2-dependent processes without affecting ATP hydrolysis and interfering with ciliogenesis . Target: Hedgehog/Smoothened. Smiles:...

Application:	Dynein inhibitor
CAS	2222768-84-3
MW:	431.5 D

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Dynarrestin

Item number: Cay35527-1

Dynarrestin is an inhibitor of dynein 1 and -2. It inhibits dynein 1-dependent microtubule gliding (IC50 = 5 µM) and dynein 2-dependent intraflagellar transport in mIMCD-3 inner medullary collecting duct cells when used at concentrations of 0.125 and 1.25 µM. Dynarrestin decreases the number of cells in metaphase,...

Keywords:	4-[4-(diethylamino)phenyl]-2-[(2,4-difluorophenyl)amino]-5-thiazolecarboxylic acid, ethyl ester
Application:	Dynein inhibitor
CAS	2222768-84-3
MW:	431.5 D

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