4 products were found matching "221877-54-9"!
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Zotarolimus
Item number: Z0818.5
Zotarolimus (also known as ABT-578) is an analogue of rapamycin (sirolimus) that was designed to have a shorter in vivo half-life than rapamycin. Zotarolimus was found to be comparable in potency for inhibiting in vitro proliferation of both rat and human T cells and mechanistically similar to sirolimus in having...
| CAS | 221877-54-9 |
| MW: | 966.21 |
707.00€
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Zotarolimus
Item number: Cay29246-1
Zotarolimus is a macrocyclic lactone immunosuppressant and a derivative of rapamycin (Cay-13346). It binds to FKBP prolyl isomerase 1A (FKBP12, IC50 = 2.57 nM) and inhibits proliferation of human peripheral blood mononuclear cells (PBMCs), rat splenocytes, and human coronary artery smooth muscle cells (IC50s = 7,...
| Keywords: | A-179578, ABT-578, (42S)-42-deoxy-42-(1H-tetrazol-1-yl)-rapamycin |
| Application: | Macrocyclic lactone immunosuppressant |
| CAS | 221877-54-9 |
| MW: | 966.2 D |
From 51.00€
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Zotarolimus
Item number: TGM-T6033-10mg
Description: Zotarolimus (ABT-578), an analogue of rapamycin, inhibits FKBP-12 (IC50= 2.8 nM). Target: mTOR. Smiles:...
| Keywords: | ABT-578, A 179578 |
| Application: | Targets serine/threonine-protein kinase mTOR [EC:2.7.11.1] (MTOR, FRAP, TOR) |
| CAS | 221877-54-9 |
| MW: | 966.21 D |
From 33.00€
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Zotarolimus
Item number: Z0818.1
Zotarolimus (also known as ABT-578) is an analogue of rapamycin (sirolimus) that was designed to have a shorter in vivo half-life than rapamycin. Zotarolimus was found to be comparable in potency for inhibiting in vitro proliferation of both rat and human T cells and mechanistically similar to sirolimus in having...
| CAS | 221877-54-9 |
| MW: | 966.21 |
365.00€
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