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Elexacaftor
Item number: TGM-T14935-100mg
Description: Elexacaftor (VX-445) is a modulator of cystic fibrosis transmembrane conductance regulator (CFTR) and it also facilitates the processing and trafficking of CFTR to increase the amount of CFTR at the cell surface. Target: Autophagy, CFTR. Smiles:...
| Keywords: | VX-445 |
| Application: | Targets cystic fibrosis transmembrane conductance regulator [EC:5.6.1.6] (CFTR, ABCC7) |
| CAS | 2216712-66-0 |
| MW: | 597.65 D |
From 88.00€
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Elexacaftor
Item number: Cay35307-1
Elexacaftor is a corrector of the cystic fibrosis transmembrane conductance regulator (CFTR) bearing the F508 deletion (F508del) mutation, which is carried by 90% of cystic fibrosis patients, and a CFTR potentiator., It increases CFTR levels in bronchial epithelial cells isolated from patients with F508del-CFTR...
| Keywords: | VX-445,... |
| Application: | F508del-CFTR corrector / potentiator |
| CAS | 2216712-66-0 |
| MW: | 597.7 D |
From 107.00€
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