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SU 0268
Item number: Cay36064-1
SU 0268 is an inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1, IC50 = 0.059 µM). It is selective for OGG1 over the DNA repair enzymes MTH1, dUTPase, NUDT16, ABH2, ABH3, and SMUG1 at 20 µM. SU 0268 (0.5 µM) inhibits OGG1 and increases the number of 8-oxoguanine DNA lesions in HeLa cell lysates.Formal Name:...
| Keywords: | 4'-[[[1-(cyclopropylcarbonyl)-1,2,3,4-tetrahydro-7-quinolinyl]amino]sulfonyl]-[1,1'-biphenyl]-3-carboxamide |
| Application: | OGG1 inhibitor |
| CAS | 2210228-45-6 |
| MW: | 475.6 D |
From 45.00€
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SU0268
Item number: TGM-T9119-100mg
Description: SU0268 is a potent and specific 8-Oxoguanine DNA glycosylase 1 (OGG1) inhibitor that regulates inflammatory responses during Pseudomonas aeruginosa infection. Target: Others. Smiles: NC(=O)c1cccc(c1)-c1ccc(cc1)S(=O)(=O)Nc1ccc2CCCN(C(=O)C3CC3)c2c1. References: Ling Zhang, et al. OGG1 co-inhibition...
| Application: | OGG1 inhibitor |
| CAS | 2210228-45-6 |
| MW: | 475.56 D |
From 39.00€
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