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3alpha-Aminocholestane
3alpha-Aminocholestane

Item number: TGM-T14037-1mg

Description: 3alpha-Aminocholestane (5alpha-Cholestan-3alpha-amine) is a potent inhibitor of inositol-5'-phosphatase 1 (SHIP1) containing the SH2 structural domain (IC50 : 2.5 µM) for research and immune-related diseases. Target: Phosphatase. Smiles:...
Keywords: 5alpha-Cholestan-3alpha-amine
Application: SHP-1 inhibitor
CAS 2206-20-4
MW: 387.68 D
49.00€ *
Review
3alpha-Aminocholestane
3alpha-Aminocholestane

Item number: Cay27885-1

3alpha-Aminocholestane is an inhibitor of SH2 domain-containing inositol-5'-phosphatase 1 (SHP-1, IC50 = ~2.5 µM). It is selective for SHP-1 over SHP-2 and phosphatase and tensin homolog (PTEN, IC50s = >20 µM). 3alpha-Aminocholestane induces hyperactivation of the tyrosine kinase SYK in patient-derived Ph+ acute...
Keywords: 3AC, (3alpha,5alpha)-cholestan-3-amine
Application: SHP-1 inhibitor
CAS 2206-20-4
MW: 387.7 D
From 44.00€ *
Review