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(±)-SHIN2
Item number: Cay44652-1
(±)-SHIN2 is a racemic mixture of (+)-SHIN2, a serine hydroxymethyltransferase 1 (SHMT1) and SHMT2 inhibitor, and (-)-SHIN2, the inactive isomer of (+)-SHIN2. Formal Name: 6-amino-1,4-dihydro-4-[3-(hydroxymethyl)-5-(5-hydroxy-1-pentyn-1-yl)phenyl]-3-methyl-4-(1-methylethyl)-pyrano[2,3-c]pyrazole-5-carbonitrile. CAS...
| Keywords: | 6-amino-1,4-dihydro-4-[3-(hydroxymethyl)-5-(5-hydroxy-1-pentyn-1-yl)phenyl]-3-methyl-4-(1-methylethyl)-pyrano[2,3-c]pyrazo... |
| Application: | SHMT1/SHMT2 inhibitor/inactive isomer racemic mixture |
| CAS | 2204289-53-0 |
| MW: | 406.49 D |
From 73.00€
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(Rac)-SHIN2
Item number: TGM-T72984-1mg
Description: (Rac)-SHIN2, a serine hydroxymethyltransferase (SHMT) inhibitor, enhances NOTCH1-driven in vivo survival of primary T-ALL in mice and is useful for studying T-cell acute lymphoblastic leukemia (T-ALL). Target: Others. Smiles: N#CC1=C(OC=2NN=C(C2C1(C=3C=C(C#CCCCO)C=C(C3)CO)C(C)C)C)N. References: Mootha...
| CAS | 2204289-53-0 |
| MW: | 406.48 D |
From 79.00€
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