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MPEP (hydrochloride)
MPEP (hydrochloride)

Item number: Cay14536-50

Glutamate, the major excitatory neurotransmitter in the brain, acts on both ionotropic and metabotropic glutamate receptors. Excessive metabotropic glutamate receptor (mGluR) transmission has been linked to epilepsy, ischemia, pain, anxiety, and depression. Eight subtypes (1-8) and multiple splice variants of the...
Keywords: 2-methyl-6-(2-phenylethynyl)-pyridine, monohydrochloride
Application: mGlu5a receptor antagonist
CAS 219911-35-0
MW: 229.7 D
From 67.00€ *
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MPEP hydrochloride
MPEP hydrochloride

Item number: TGM-T2497-100mg

Description: MPEP hydrochloride is an effective and highly specific non-competitive antagonist at the mGlu5 receptor subtype (IC50: 36 nM). Target: GluR. Smiles: Cl.Cc1cccc(n1)C#Cc1ccccc1. References: Inta Dragos, et al. Neuropharmacology (2012), 62(5-6), 2034-2039.
Application: mGlu5a receptor antagonist
CAS 219911-35-0
MW: 229.7 D
From 40.00€ *
Review