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Item number: TGM-T2642-100mg

Description: PD173074 is an effective FGFR1 inhibitor (IC50: 25 nM) and also inhibits VEGFR2 (IC50: 100-200 nM) in cell-free assays. The selectivity is higher ~1000-fold for FGFR1 than PDGFR and c-Src. Target: Apoptosis, EGFR, IGF-1R, Src, FGFR, VEGFR. Smiles:...

CAS	219580-11-7
MW:	523.67 D

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PD 173074

Item number: Cay13032-5

The fibroblast growth factor receptors (FGFRs) are cell surface receptors with intrinsic tyrosine kinase activity, which is necessary for receptor activation and signal propagation. PD 173074 is a potent and selective inhibitor of FGFR tyrosine kinase activity, blocking autophosphorylation of FGFR1 with an IC50...

Keywords:	N-[2-[[4-(diethylamino)butyl]amino]-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)-urea
Application:	FGFR inhibitor
CAS	219580-11-7
MW:	523.7 D

From 54.00€ *

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