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Item number: Cay15395-1

Heat shock protein (Hsp) inhibitor I is a benzylidene lactam compound that prevents the synthesis of inducible Hsps Hsp105, Hsp72, and Hsp40. At 100 µM, it can inhibit the development of thermotolerance in COLO 320 DM cells. Its effects on thermotolerance have been studied in the context of clinical fractionated...

Keywords:	Hsp Inhibitor I, KNK 437, 3-(1,3-benzodioxol-5-ylmethylene)-2-oxo-1-pyrrolidinecarboxaldehyde
Application:	HSP105 / HSP72 / HSP40 induction inhibitor
CAS	218924-25-5
MW:	245.2 D

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KNK437

Item number: TGM-T2444-100mg

Description: KNK437 (Heat Shock Protein Inhibitor I), a pan-HSP inhibitor, suppresses the synthesis of inducible HSPs(HSP105, HSP72, and HSP40). Target: HSP. Smiles: O=CN1CCC(=Cc2ccc3OCOc3c2)C1=O. References: Yokota S, et al. Cancer Res. 2000, 60(11), 2942-2948.

Keywords:	Heat Shock Protein Inhibitor I
CAS	218924-25-5
MW:	245.23 D

From 33.00€ *

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