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APS6-45
APS6-45

Item number: Cay38417-1

APS6-45 is an inhibitor of RETM918T and a derivative of sorafenib (Cay-10009644, Cay-35612). It selectively binds to RETM918T over Eph tyrosine kinase receptor A8 (EphA8), p38delta, JNK2, and c-Src (Kds = 28, 410, 940, 1,500, and 1,700 nM, respectively), as well as a panel of over 60 kinases at 10 µM, but also binds...
Keywords: 4-[4-[[[[2-fluoro-5-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridine...
Application: RET-M918T inhibitor, sorafenib
CAS 2188236-41-9
MW: 548.4 D
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