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Item number: Cay36293-1

CB-103 is an inhibitor of Notch signaling. It binds to the b-trefoil domain (BTD) of recombination signal binding protein for immunoglobulin kappa J region (RBPJ) and inhibits the assembly of the RBPJ-Notch intracellular domain (NICD) transcription complex. CB-103 inhibits ligand-induced Notch signaling in HeLa...

Keywords:	6-[4-(1,1-dimethylethyl)phenoxy]-3-pyridinamine
Application:	Notch signaling inhibitor
CAS	218457-67-1
MW:	242.3 D

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