Description: Metapramine (19560 RP) is a novel psychostimulant, an N-methyl-D-aspartate receptor (NMDA) antagonist with antidepressant and anti-injury perception activity that promotes increased levels of acetylcholine in the striatum. Target: Dehydrogenase. Smiles: C=1C=CC2=C(C1)N(C=3C=CC=CC3C(NC)C2)C. References:...

An antidepressant, decreases action potential amplitude and maximal signal velocity and increases conduction time in isolated dog Purkinje fibers at 10 µM, reduces ethanol consumption in ethanol-preferring rats at 10 mg/kg, inhibits reperfusion-induced increases in ventricular arrhythmias in a rat model of...