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Item number: Cay42125-10

An M4 muscarinic receptor PAM, selective for M4 mAChRs over a panel of 59 receptors, ion channels, transporters, and enzymes at 10 µM, selectively potentiates ACh-induced activation of the M4 mAChR over M1-M3 and M5 mAChRs in cells expressing the human receptors (EC50s = 12.3, 4,798, >10,000, >10,000, and >10,000...

Keywords:	CVL-231, PF-06852231,...
Application:	M4 muscarinic receptor positive allosteric modulator (PAM)
CAS	2170722-84-4
MW:	390.4 D

From 557.00€ *

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Emraclidine

Item number: TGM-T9694-100mg

Description: Emraclidine (CVL-231), a muscarinic M4 receptor positive allosteric modulator, is utilized in studies of neurological diseases. Target: AChR. Smiles: Cc1cc(C)c2CN(Cc2n1)C(=O)CC1CN(C1)c1ccnc(c1)C(F)(F)F. References: Lei Zhang, et al. 5,7-dihydro-pyrrolo-pyridine derivatives for treating neurological and...

Keywords:	CVL-231
Application:	Targets muscarinic acetylcholine receptor M4 (CHRM4)
CAS	2170722-84-4
MW:	390.4 D

From 122.00€ *

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