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CX-546
CX-546

Item number: Cay45130-10

An AMPA receptor positive allosteric modulator, attenuates desensitization and slows deactivation of GluA1 and GluA2, increases AMPA-stimulated glucose utilization in cortical astrocytes (EC50 = 93.2 µM), reduces mechanical and cold allodynia and immobility time in the forced swim test in rat model of SNI-induced...
Keywords: (2,3-dihydro-1,4-benzodioxin-6-yl)-1-piperidinyl-methanone
Application: Positive allosteric AMPA receptor modulator
CAS 215923-54-9
MW: 247.29 D
From 97.00€ *
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CX546
CX546

Item number: TGM-T7580-100mg

Description: CX546 is an AMPA receptor modulator. CX546 enhances cognitive function in rats. It has also been proposed as a treatment for schizophrenia. Target: Autophagy, iGluR. Smiles: O=C(N1CCCCC1)c1ccc2OCCOc2c1. References: Pellerin L , Magistretti P J . Ampakine CX546 bolsters energetic response of astrocytes:...
CAS 215923-54-9
MW: 247.29 D
From 33.00€ *
Review